Domino's signature hand-tossed crust with robust tomato sauce, mozzarella and pepperoni. The pizza that built the world's most successful delivery empire โ from a single Michigan store in 1960.
The Domino's Large Pepperoni (Hand Tossed) contains 2560 calories, 112g of protein and 104g of fat. It costs $14.49 in the United States, up from $0.99 in 1960. Available in 34 countries, with prices ranging from $4.35 in Egypt to $17.68 in Sweden. This page covers full Large Pepperoni (Hand Tossed) nutrition facts, price history, and worldwide price comparison.
Add to your order, pick a delivery platform, and see the full cost including fees, taxes and tip โ in any of 34 countries.
Start Building โยฉ 2026 PriceMyMeal. Prices are approximate and may vary by location. Not affiliated with Domino's.